Sentence examples for regulate the clearance from inspiring English sources

Furthermore, use of nanoparticles and microparticle for immune therapies and vaccines is becoming an important aspect of treating several diseases [34]; however, the immune molecules that regulate the clearance and delivery of these antigens have not been clearly established.

Which factors regulate the clearance of the immune cells after the immune reaction has been completed?

The enhanced oxidative stress tolerance is associated with significant upregulation of antioxidant genes and a significant increase in the adipose tissue of FoxO3a, a transcription factor that is known to regulate the clearance of ROS (10).

Since MnSOD closely regulates the clearance of ROS in the mitochondria and we observed an up-regulation of MnSOD by IL-6 treatment, flow cytometry was performed to detect IL-6- and/or IR-induced mitochondrial oxidant generation (presumably O2−) in myeloma cells [ 26].

Interplay between autophagy, LAP, and phagocytosis regulates the clearance of dying cells.

For example, Parkin is recruited to mitochondria via PINK1 on membrane depolarization, and regulates the clearance of damaged mitochondria by mitophagy in mammalian cell lines.

Thus, it appeared unlikely that DNT1 constructs were regulating the clearance or aggregation of Aβ in the fly brain and so alternative mechanisms were investigated in mammalian cell culture.

The expression of p62/Sequestosome 1, an adaptor protein that regulates the clearance of select ubiquitinated substrates (Korolchuk et al, 2009) was studied, as it accumulates during the inhibition of autophagy (Bjørkøy et al, 2005).

We have established that autophagy regulates the clearance of mutant huntingtin (htt) fragments and other aggregate-prone proteins, and that the percentage of cells with aggregates of mutant htt correlates inversely with autophagic activity, all other things being equal 27, 28.

Also, it is unknown whether MUL1 interacts with the PINK1/parkin pathway to regulate the mitochondrial clearance.

During the tubular phase, Organic Anion Transporters (OAT1 and OAT3) are involved in the intracellular accessing of TDF, on the other hand, Multidrug Resistance associated Protein (MRP2 and MRP4) regulate the extracellular clearance of the drug [ 19].