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Conversely, one might imagine that the Midgut Junction DH31 expressing cells may secrete a different signal to regulate secretion of AllostatinB/MIP, which had myoinhibitory activity [ 74] from neighbouring enteroendocrine cells in the junction (Fig 5B).
Therefore, these results clearly showed that Kif4A mediated recruitment of macrophage in co-culture system via regulate secretion of CCL2 in both Cal-27 cells and THP-1-derived macrophages and expression of CCR2 on macrophages.
Although all PKDs are regulated by a DAG-binding C1 domain and by an activation loop, they have been shown to regulate secretion of different cargo molecules.
The same group also demonstrated that c-di-GMP levels that are lowered in a phosphate limiting environment, regulate secretion of the adhesin LapA required for biofilm formation by Pseudomonas fluorescens and further extended the biological roles of c-di-GMP beyond regulation of exopolysaccharide production and motility [41].
In Leishmaniasis, the CD40-CD40L signaling has been proposed to regulate secretion of two counter regulatory cytokines, IL-12 and IL-10 via the p38 MAPK and ERK pathway, by skewing the CD40 signaling towards ERK 1/2, which then induces IL-10; in turn, the increased IL-10 prevents CD40 induced p38 MAPK activation, translating into a reduction in IL-12 [40] [40].
Similarly, human neutrophils have several different SNAREs that regulate secretion of specific granules [129].
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Sieburth, D., Madison, J. M. & Kaplan, J. M. PKC-1 regulates secretion of neuropeptides.
Tsunemi T, Hamada K, Krainc D. ATP13A2/PARK9 regulates secretion of exosomes and alpha-synuclein.
Capsules subcutaneously implanted in DBA/2J mice demonstrated a tightly regulated secretion of EPO through up to four on off cycles during a period lasting 40 weeks.
The Ca2+ receptor on parathyroid cells, because it is the primary mechanism regulating secretion of parathyroid hormone (PTH), is one such target.
Glucagon-like peptide-1 (GLP-1) controls glucose homeostasis by regulating secretion of insulin and glucagon through a single GLP-1 receptor (GLP-1R).
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