Sentence examples for regulate receptor function from inspiring English sources
In this review, we provide a summary of functional studies in the context of the post-structure era, aiming to clarify our understanding of the way in which P2X receptors function in response to ATP binding, as well as the mechanism by which allosteric modulators are able to regulate receptor function.
Amino acids known to regulate receptor function are linked through packing interactions and a network of hydrogen bonds, suggesting a conformational pathway from the ligand-binding pocket to regions that interact with G proteins.
In addition to its effects on M2 receptor trafficking, RACK1 could regulate receptor function in other ways.
The role of phosphorylation in regulating receptor function dramatically extends the range of regulatory control of this important covalent modification.
We compare and contrast the profile of anesthetic steroids with that of sulfated steroids that negatively regulate GABAA receptor function.
This study provides a new molecular mechanism by which group-I mGluRs could dynamically regulate NMDA receptor function.
7 Several kinases have been suggested to phosphorylate the CTDs of GluN2A and GluN2B and thereby regulate NMDA receptor function.
This effect of CXCL12 is blocked by cotreatment with AMD3100, suggesting that CXCR4 stimulation may regulate NMDA receptor function.
Alternatively, microglia may secrete as yet unidentified NMDA antagonists or secrete cytokines that regulate NMDA receptor function or density.
Small molecules that selectively inhibit Hh protein biogenesis or Ptch1 activity, regulate Fzd receptor function, activate TGFβ signaling pathways, actuate FGFRs, or abrogate NICD/CSL function, to name a few examples, would be especially desirable.
As arrestin3 expression is enhanced in mesenteric vessels and MSMCs from 12-wk-old SHR, and both proteins are known to regulate ETA receptor function (22), we have also examined whether developing hypertension has effects on ET1-induced PLC signaling.
