Sentence examples for regulate phase from inspiring English sources

To understand how xenobiotics regulate phase II enzyme expression, acrylamide was selected as a model xenobiotic chemical, as it induces a large number and a variety of phase II enzymes, including numerous glutathione S-transferases (GSTs) in Caenorhabditis elegans.

PXR is known to regulate Phase I enzyme subfamilies CYP3A, CYP2B, and CYP3A in the human and rodent liver.

Thus, although increased SKN-1 activity can extend lifespan [ 4, 13], the ability to regulate phase 2 detoxification gene expression in response to changes in the environment may also be important.

T cell development involves a series of sequential developmental steps requiring instructions from the specialised thymic microenvironment to regulate phases of proliferation, gene rearrangement and selection [ 18, 19].

Progesterone withdrawal regulates phase one of menstruation, by up-regulating local cytokine presence (Hannan et al., 2004; Jones et al., 2004).

The NF-E2-related factor-2 (Nrf2)/antioxidant response element (ARE) signaling pathway regulates phase 2 detoxification genes, including a variety of antioxidative enzymes.

Estradiol inhibits Cl- secretion in the CF lung and up-regulates mucus production, which may be very relevant in CF. Cigarette smoke is de-toxified through Phase I and Phase II enzymes and estrogens may preferentially up-regulate Phase I enzymes, leading to accumulation of toxic metabolites through a process called bioactivation.

10.7554/eLife.06253.006 Figure 2. Glucagon (GCG) receptor regulates phase resetting effects of OXM and GCG in Per2::LUC liver slices.

It can be hypothesized that gene products regulating phase I and II enzymes [ 15, 44, 45], tumor suppressor genes [ 46] and DNA repair genes [ 47- 49] are associated with the development of lung cancer, but results are contradictory.

The miRNAs with the best-defined roles in regulating phase changes in the shoot meristem are miR156 and miR172 which form a regulatory module that is widely conserved in plants.

During cell cycles, cyclin-dependent kinases (Cdks) regulate G1 phase transitions to S phase.