Exact(23)
Most of the predicted regulators belonged to the protein families whose members were known to regulate pathways for carbohydrate metabolism, such as the AraC, GntR, LacI, and ROK families [ 46- 49].
miRNAs can regulate pathways involved in aging, and are significantly up- or down-regulated in their expression levels [ 19].
Of the ~20 candidate genes in the region, Prkca, which encodes Protein Kinase C-alpha, is a plausible candidate because it is a well-known regulator of immune responses in the lung [ 52] and therefore may regulate pathways that in turn affect miRNA expression.
This approach requires the identification of compounds that regulate pathways and bind to proteins with high specificity.
However, some other attempts to regulate pathways had totally different results.
For example, intratumoral hypoxia can increase hypoxia inducible factor 1 alpha (HIF-1α), which may regulate pathways that contribute to radiation sensitization or radiation resistance.
Similar(37)
To examine this huge amount of regulated transcripts, we decided to apply global pathway analysis to identify significantly regulated pathways.
Mujahid S, Logvinenko T, Volpe MV, Nielsen HC. miRNA regulated pathways in late stage murine lung development.
Finally increased levels of MAPK14 and HIF-2α suggest an impact of pH on kinase and HIF regulated pathways.
Our results suggest that absence of adequate Ca2+ signaling through nuclear CaMKII regulated pathways leads to development of cardiac disease.
Our results suggest that MDP regulated pathways are inhibited in CARD15 non-mutated CD monocytes.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com