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PPARγ also may regulate neuronal responses to ischemia since conditional deletion of PPARγ in neurons increases their susceptibility to ischemia in vitro (Zhao et al., 2009).
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This literature is most prevalent in the brain where caspase-1 may directly regulate neuronal cell death in response to diverse insults.
Furthermore, Armcx1 knockdown undermines both neuronal survival and axon regeneration in the high regenerative capacity model, further supporting a key role of Armcx1 in regulating neuronal injury responses in the adult central nervous system (CNS).
Glutamate-induced Ca2+ oscillations and waves coordinate astrocyte signaling responses, which in turn regulate neuronal excitability.
Members of the K2P potassium channel family regulate neuronal excitability and are implicated in pain, anaesthetic responses, thermosensation, neuroprotection, and mood.
Musiek, E. S. et al. Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration.
Li, Y. H., Werner, H. & Puschel, A. W. Rheb and mTOR regulate neuronal polarity through Rap1B.
Our previous studies have demonstrated that srGAP3 can negatively regulate neuronal differentiation of Neuro2a cells.
We found that all three TET proteins could negatively regulate neuronal differentiation of Neuro2a cells.
Furthermore, non-catalytic TET1 could negatively regulate neuronal differentiation through upregulating srGAP3.
3 VGSCs also regulate neuronal growth and migration.
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