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Moreover, activation of the BLA was shown to regulate neural plasticity in the DG [34], [35], the former being also associated with stress-induced deficits in hippocampal long-term potentiation (LTP) and spatial memory in rats [36], [37].
As such technologies are becoming widely available, it is very likely that there will be a rapid acceleration of our knowledge of how, where and why mitochondria respond to and regulate neural plasticity and how abnormalities in such mechanisms contribute to the pathogenesis of neurological disorders.
Several signalling molecules known to regulate neural plasticity also modify mitochondrial biogenesis; examples include nitric oxide, oestrogen, and growth factors, including BDNF, EGF (epidermal growth factor) and bFGF (basic fibroblast growth factor; Barsoum et al., 2006; Gutsaeva et al., 2008; Klinge, 2008; Hebert et al., 2009; Renton et al., 2010).
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Ephrin ligands and receptors guide axons during neural development and regulate neuronal plasticity in adults [ 55, 56].
Astrocytes contribute to synaptogenesis and dynamically modulate information processing and signal transmission, regulate neural and synaptic plasticity, and provide trophic and metabolic support to neurons as well as the BBB.
Numerous miRNAs are expressed at high levels in the nervous system; a few of these have been localized to dendrites (Kye et al, 2007), where they are believed to regulate neural development and plasticity.
Additionally, we found that mir-134 expression was decreased in LDW compared to SD. miR-134 has been shown to regulate neural stem cell proliferation and neural plasticity, however, in a direction seemingly contradictory to our results.
How Does The Sleep/Wake Cycle Regulate The Neural Plasticity Mechanisms that Impact Learning?
For example, the Ras-MAPK signaling pathway controls cell proliferation and differentiation at the embryonic stage [ 6- 8] and regulates synaptic formation required for neural plasticity at the adult stage [ 9].
Using Closed-Loop Real-Time fMRI Neurofeedback to Induce Neural Plasticity and Influence Perception.
poster: Using Closed-Loop Real-Time fMRI Feedback to Induce Neural Plasticity & Influence Perception.
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