Sentence examples for regulate modification from inspiring English sources
This potential activity of Not4 toward mRNA processing and export factors may regulate modification of their function through mono-ubiquitination or target them for degradation through poly-ubiquitination.
PmrA/B control only a subset of the genes that regulate modifications of the LPS, and pmrA mutants remain resistant to some antimicrobial peptides such as cathelicidin.
Additional protein lipid, and lipid lipid interactions provide regulated modification of ER membrane phospholipid composition which are required to support the cooperative interactions required for selective transport.
Still, aberrant modifications are observed in diseased cells, and the enzymes that regulate histone modification have become important targets in drug development programs.
If PHB modification is needed for the functioning of many proteins, it might be expected that mechanisms would have evolved to regulate such modification.
Other rules regulate the modification of ongoing contractual relations with a view to preventing a party with considerable bargaining power from unfairly imposing changes in the contract.
Enzymes such as histone acetylases and histone deacetylases regulate histone modification by adding or retracting acetyl groups and thereby closing or opening accessibility of the nucleosome.
The Bur complex also acts by targeting non-CTD substrates to regulate histone modification [33], [34] and to suppress cryptic transcription [35].
Our findings confound existing views and point to active cellular mechanisms which dynamically regulate histone modification levels and account for exon-intron marking.
As part of mSin3A-HDAC corepressor complexes, ING2 binds to tri-methylated lysine 4 of histone H3 (H3K4me3) to regulate chromatin modification and gene expression.
With suggestive SNPs in genes for p53 and CDKN2A [9]], [9], which also regulate histone modification, evidence for a role of inherited risk factors related to histones is accumulating.
