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HA-receptor downstream signaling pathways regulate in turn cellular processes implicated in tumorigenesis.
Plk1 and Plk3 regulate in turn p53 activation and Cdc25c transcription, translation and phosphorylation (Fig. 7).
Indeed, our results suggest that enzastaurin has a direct effect on E2F-1, which regulate in turn the transcription of several genes, including TS. E2F-1 mRNA expression was significantly reduced by enzastaurin treatment, whereas pemetrexed increased E2F-1 mRNA levels.
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Wark noted that the rise of civil society necessitated at its earliest stages new forms of media through the personal essay – each of which have had to be regulated in turn by the state.
Insect JH is regulated, in turn, by insulin-like signaling (IIS).
LHs modulate outcomes based on binding to chromatin, regulated in turn, by modifications of chromatin or LHs themselves.
These sites appear to bind both E2F1 and E2F4 and may be regulated in turn by interaction with p130/p107.
It needs to be determined whether genetic, post-transcriptional or translational mechanisms; regulated in turn by molecules governing KIT expression, underlie these observations.
Akt is regulated in turn by phosphatidylinositol 3-kinase (PI3K), which is a transducer of growth factor effects on cell survival [ 40, 41].
While elevated levels of apoB and reduced levels of apoA1 are associated with increased cardiac disease, serum levels of apoB100 associated VLDL are regulated in turn by Acat2 which stimulates cholesteryl ester secretion into apoB-containing lipoproteins.
Examples exist to support the notion that subcellular localization of CHIP is regulated and in turn can regulate its functional activity.
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