Sentence examples for regulate gene function from inspiring English sources

We hypothesize that polymorphic markers associated with Lim3A expression are located within the binding sites for proteins that regulate gene function, and provide general rather than tissue-specific regulation of transcription, and that intermediate levels of Lim3A expression confer a selective advantage and longer lifespan.

Akin to alternative splicing, alternative translation of polycistronic messages is a mechanism to generate protein diversity and regulate gene function.

When combined with genomic data, proteomics may enable a deeper understanding of complex mechanisms that regulate gene function and dysfunction in cancer.

Epigenetics is the study of molecular factors and processes that regulate gene function independently of alterations in the DNA sequence [ 143].

MicroRNAs (miRNAs) are small endogenous noncoding RNAs that regulate gene function in a manner specific to cell type and developmental stage [ 19– 23].

Thus, processes such as transcription must be mediated by mechanisms that regulate gene function rapidly and reliably (Barrera and Ren, 2006; Kornberg, 2007).

Since chloroplasts can be considered a population within the cell, major-allelic variations that change amino acid sequences and translation efficiencies may affect or regulate gene functions.

Therefore, lncRNAs acting together with chromosomal proteins are thought to regulate gene functions in an RNA-RNA hybridization-independent manner.

miRNAs regulate gene functions mainly through degradation of their cognate mRNAs by perfect matches with the mRNA molecules; or via inhibition of protein translation through base pairing of ~7 nucleotides (called "seed sequence") between miRNA and the 3'-untranslated region (3'-UTR) of the target mRNA molecules [ 8].

Stephen Baylin, deputy director of the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, will co-lead with Peter A. Jones, director of the University of Southern California/Norris Comprehensive Cancer Center a $9.12 million three-year grant to study epigenetic changes that modify the way a cell packages its DNA sequence for regulating gene function.

Thus, the importance of CREB in regulating gene function and integrating physiological signals makes it an interesting molecular target to possibly overcome problems caused by early alcohol exposure.