This study shows that regulating the electron flow to the heme of human cytochrome P450 CYP3A4, using artificial redox chains, can significantly enhance its coupling efficiency and catalytic activity at electrode surfaces.
Besides these two regulatory mechanisms identified to facilitate the flow of Cu to the thylakoid lumen under limiting Cu, the enzymatic properties of HMA8 (high affinity for Cu- and PC-dependent turnover rate) may be an additional way to regulate the flux of Cu into PC and thus to regulate the photosynthetic electron flow.
Therefore, the inhibition of the AOX pathway down-regulated the photosynthetic electron flow not only by the loss of the sink of excess reducing equivalents but also by the production of certain biochemical signals.
ADP + Mg2+ (5 mM) were subsequently added to determine maximal electron flow through electron-transferring flavoprotein and fatty acid oxidative capacity.
The copper binding peptide methanobactin is not only suspected to be involved in copper acquisition from the extracellular phase [10, 17], but it may also function as copper chaperone for pMMO [8, 10, 19], be responsible for the electron flow to pMMO [19 21], and regulate pMMO expression [10, 20].
Joliot, P. & Johnson, G. Regulation of cyclic and linear electron flow in higher plants.
In the context of this study, the hydrogenase is probably acting to regulate the flow of electrons through the photosynthetic electron transport chain.
The organisms try to minimize this process by regulating the excitation pressure on the PSII reaction center chlorophylls, optimizing the electron flow in the photosynthetic electron transport chain and quenching chlorophyll triplet states and O2.
For example, phenazines modify cellular redox state, act as electron shuttles altering electron flow patterns, contribute to biofilm formation and architecture, act as cell signals that regulate patterns of gene expression, and contribute to the survival of the producer.
We examined electron flow from electrodes into Shewanella to determine the feasibility of this process, the molecular components of reductive electron flow, and what driving forces were required.
A simple example would be the "electron flow" image series I've made.
