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Thus, RACK1 functions as an endogenous inhibitor of the Src kinase in diverse signaling pathways that regulate distinct cellular functions.
These results suggested that the three miRNAs regulate distinct cellular signaling pathways.
Collectively, our in vitro, in vivo and in silico experiments show that TWEAK differentially affects the expression of various miRNAs which regulate distinct cellular responses.
mTORC1 and mTORC2 phosphorylate different substrates to regulate distinct cellular functions.
Thus, activation of P2X7R may also activate different intracellular signaling mechanisms to regulate distinct cellular functions in various types of cells.
miRNAs are highly conserved, endogenous noncoding RNAs that have been shown to regulate distinct cellular processes by interfering with protein expression at the post-translational level.
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How pHi responds to and regulates distinct cellular processes has primarily been determined by evaluating protein activities.
Different Rab proteins are localized in cellular compartments and regulate distinct vesicles and endosome transport routes.
Thus, a reasonable explanation is that DR and IIS regulate distinct targets that have opposing effects on cellular stress and body size.
Alternatively, HOXC9 could directly regulate distinct sets of genes to coordinate the cellular events associated with differentiation.
Different NCS proteins can regulate distinct target proteins, and they can have highly specific, or more wide-ranging, distributions and cellular roles [1].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com