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These results suggest that miRNA target genes can be either up-regulated or down-regulated in myeloid cells to regulate differentiation of the myeloid cells.
We are also examining whether similar regulation of B7h by TLR ligands occurs on dendritic cells that regulate differentiation of T cells.
Biologists find that long non-coding RNA molecules are necessary to regulate differentiation of embryonic stem cells into cardiac cells.
Gatto, D. et al. Complement receptors regulate differentiation of bone marrow plasma cell precursors expressing transcription factors Blimp-1 and XBP-1.
The Caudal-related homeobox genes Cdx1 and Cdx2 are intestine-specific transcription factors that regulate differentiation of intestinal cell types.
The present study was designed to study whether small heterodimer partner-interacting leucine zipper protein (SMILE), a novel co-repressor, could regulate differentiation of adipocyte in 3T3-L1 cells.
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Platelet-derived CXCL12 differentially regulates differentiation of CD34+-progenitor cells into a macrophage and foam cell phenotype.
BMP regulates differentiation of various types of cells, but its main target is the regulation of osteoblast differentiation.
The transcription factor RORγt regulates differentiation of the TH17 subset of helper T cells, thymic T cell development and lymph-node genesis.
Since the chromatin modifier CBP regulates differentiation of neuronal precursors via its HAT activity2, we investigated whether CBP could modulate the mitochondrial biomass of PC12-ND6 cells.
Lee, K. et al. Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways.
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