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The first attempts to regulate competitive ice hockey matches came in the late 1880s.
Classical ecological analyses, from Lotka-Volterra to Tilman's R* to contemporary models [2] [5], typically (implicitly) assume that competing species are fixed for the attributes that regulate competitive dynamics, i.e., that ecological dynamics are much faster than evolutionary change.
During performance across tasks as well as during rest and rumination, the AIC has been argued to regulate competitive dynamics between large-scale networks (Sridharan et al. 2008).
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This is because policies offered on the highly regulated, competitive exchanges would probably be cheaper than comparable coverage available on today's overpriced individual market.
The latter is probably because of the action of inhibitory male steroidal cues dominated by androstenedione [ 2], which is released in large amounts through the gills of sexually active males and has been suggested to be a male pheromone regulating competitive interactions among males [ 6].
The Healthy, Hunger-Free Kids Act of 2010 authorized the Secretary of the US Department of Agriculture to establish science-based nutrition standards for competitive foods and beverages sold in school that are, at a minimum, aligned with the 2010 Dietary Guidelines for Americans (DGA), while still providing districts with discretion in regulating the competitive food and beverage environment.
For example, the full dependency graph of p90RSK2 contains 49 potential "remote targets" many of which can also be regulated by competitive pathways.
The PP pathway is regulated through competitive inhibition [ 27] and post-translational modifications via phosphorylation [ 20, 21].
Interestingly, it appears that miR-223 is selectively expressed in neutrophils and macrophages but not monocytes and lymphocytes and this process is regulated by competitive binding between transcription factors.
We found that IRF1, who plays a tumor suppressing role, is negatively regulated by competitive transcriptional binding of IRF2, both of which were significantly correlated with tumor stage (p-value 0.001), depth of tumor infiltration (p-value 0.006) and lymph node metastasis (p-value 0.015) in human esophageal cancers [ 40].
We suggest a model in which the balance between self-renewal and differentiation is regulated by competitive occupancy of the proximal promoters of key stem cell genes such as Zfp42/Rex-1, Nanog, Pou5f1(Oct4), Lefty1 and Lefty2, and others such as the Klf genes themselves.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com