Sentence examples for regulate client from inspiring English sources

Despite such importance, little is known about the biochemical characteristics that regulate client interaction and specificity.

Thus, achieving the correct balance in membrane protein triage is vital, but the mechanisms that regulate client discrimination are not well understood.

Participation of the Hsp70/Hsp40 chaperone system is also required to regulate client binding to Hsp90 (Pratt and Toft, 1997) and to load Hsp90 with a client protein (Hernández et al., 2002).

The mode of action of the chaperone is determined in this situation by cochaperones, which regulate client binding and provide a link to other folding factors or to degradation systems (Fig. 1).

Hsp70/or Hsp90/complexmight mighaveave a common mechanism to regulate client proteins in response to dynamic redox state in cells, which involves oxidative stress-induced post -translational modification on client proteins, and subsequent change in the interaction of Hsp70 or Hsp90 with client proteins.

3) Data on other "canonical" chaperones have always suggested that one requires a dynamic cycle to modulate client affinity regulated by ATP driven reactions.

Edelman's best known for their decades of work for Big Tobacco, including designing and implementing coordinated campaigns to downplay the dangers of smoking and discredit those who sought to more vigorously regulate their clients' deadly and addictive cigarettes.

We employed a targeted molecular probe approach to study modifications of the molecular chaperone heat shock protein 90 (Hsp90), which regulates diverse client proteins.

Senate Majority Leader Tom Daschle is saying the U.S. Securities and Exchange Committee chairman should be fired because he is too close to his old clients to regulate them or their clients effectively.

18 In a psychodynamic therapy based on the APT model, the therapist typically clarifies defences, helps the client to observe and experience the underlying affects and helps the client to regulate associated anxiety.

Overall, these data imply that iRhoms regulate secretion of specific client proteins, which include the EGF family of growth factors.