Results suggest that lncRNAs might regulate cell proliferation.
DR6 belongs to death receptor family which initiates cytotoxic signals or regulate cell proliferation and survival (Guicciardi and Gores, 2009).
Myeloid hematopoietic growth factors (HGF) are glycoproteins produced in different cells of the organism which regulate cell proliferation and differentiation.
P53 is a homotetrameric tumor suppressor protein involved in transcriptional control of genes that regulate cell proliferation and death.
Recent studies indicate that Pax6 regulates multiple transcriptional networks that regulate cell proliferation as well as differentiation (Farhy et al., 2013).
Bone morphogenetic proteins (BMPs) operate though autocrine and paracrine mechanisms to regulate cell proliferation, differentiation and apoptosis during development (Patel and Dressler, 2005; Varga and Wrana, 2005).
In addition, Campbell[8] had demonstrated that Lf may be down-regulated in some cancers, such as human breast carcinoma and showed that it may regulate cell proliferation.
MAX is the most conserved dimerization component of the MYC-MAX-MXD1 network, and they work as transcription factors that regulate cell proliferation, differentiation, and apoptosis [4].
Mapk, also known as extracellular signal-regulated kinases (ERKs), often plays a vital role in mediating intracellular signaling, including those to regulate cell proliferation.
Epidermal growth factor receptor (EGFR) is a cell surface receptor which plays a significant role in signaling pathways, which regulate cell proliferation, angiogenesis, and tumor metastases [8].
One major question is how N-cadherin interaction may negatively regulate cell proliferation and survival.
