Sentence examples for regulate binding to from inspiring English sources
Rather, the conformation of the RIP2 kinase domain functions to regulate binding to the XIAP-BIR2 domain.
In most cases phosphorylations of motors [8], [20], [35] or of non-motile microtubule crosslinking proteins [36] by Cdk1 negatively regulate binding to microtubules in vivo.
A mechanism for toxicity is proposed which involves receptor proteins; the planar aromatic system controls binding to cytosolic proteins and halogen substituents regulate binding to nuclear proteins.
This conformational cycle is the main driving force for the on/off 'switch' mechanism of Rabs and their ability to both regulate binding to downstream effectors and perform the desired function.
Despite numerous previous reports utilizing serine (Ser -to-alanine Ser -to-alanine Ser -to-alanine Alaosphorylandon sithreonines of 4E-BP1 Thr -to-Alahich posThr -to-Alaonal modificaThr -to-Alaectly regulate binding to eIF4E, an ambiguous understanding phosphorylation
The molecular basis for this selectivity is unknown, although a distinct possibility is that the N-terminal extension may interact with the tail domain of myosin 15 to regulate binding to cargo proteins.
This human mutation analysis suggests that regions outside that of the C terminus have a role in regulating binding to interacting proteins required for proper vision.
Whether the DNA-binding domain (DBD) of TFs alone can regulate binding affinity to DNA is an important question for identifying the design principle of TFs.
Moreover, plakoglobin phosphorylation was shown to be required for EGFR-induced loss of cell adhesion and to regulate binding of plakoglobin to desmoplakin (Miravet et al. 2003; Yin et al. 2005).
However, the role of FE65 in APP processing and the mechanisms that regulate binding of FE65 to APP are not fully understood.
Interestingly, phosphorylation of KLC1 on serine-460 has recently been shown to selectively regulate binding of calsyntenin-1 but not several other ligands to kinesin-1 motors (15).
