Cells regularly face variable environments and can sense many different signals, including temperature, oxidative, and osmotic pressure, beneficial nutrients, and harmful chemicals.
Single-celled organisms such as yeasts regularly face variable and often harsh external environments which threaten its survival or at least prevent it from performing optimally.
Briefly, linkage mapping involves scanning entire genomes of families affected by an illness using known regularly spaced variable DNA segments, thus identifying those genetic variants (alleles) that are shared by affected family members more frequently than would be expected based on chance [ 8].
This is one of a series of studies whose objective was to demonstrate and validate the creation of such an index, derived empirically from regularly collected variables available in a hospital's EHR.
This maneuver is repeated regularly with a variable interval, depending on the calculated volume status.
Continuous traces exhibit smooth trends of variables regularly observed at continuous time-scales.
Resection margin status and presence of extrahepatic metastases are two additional clinicopathological prognostic variables regularly used in clinical practice.
Few fields are regularly updated: Six variables were filled in by all offices (Year/Sequence number/Type/Thematic/Country/ Region) and two categories were not filled in by anybody (RO and HQ comments).
Alternatively in a prospective design one measures psychological variables regularly (e.g. daily or weekly), where the analytical approach could be a longitudinal repeated-measures design (e.g. time-series) or a nested case-crossover analysis.
Variables regularly documented include CRP, ESR, numbers of swollen and tender joints by using a 28-joint count (SJC28, TJC28); patient global assessment of disease activity (PGA), evaluator global assessment of disease activity (EGA), pain by visual analogue scale, and physical function by HAQ.
