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Flupirtine is administered in oral doses of up to 200 mg as often as four times a day; given a plasma half-life of about 10 h, four regularly spaced doses a day may lead to more than twofold accumulation (Friedel and Fitton, 1993).
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In these studies, mice were immunized subcutaneously with soluble antigen and adjuvant using well-defined doses and injection regimens: (i) one bolus dose, (ii) regularly spaced, equivalent doses, (iii) regular injections with exponentially decreasing doses, or (iv) regular injections with exponentially increasing doses (Fig. 4a).
Treatment of asymptomatic individuals, regardless of their malaria infection status, with regularly spaced therapeutic doses of antimalarial drugs has been proposed as a method for reducing malaria morbidity and mortality.
In general, colonies were regularly spaced at a fine scale.
Irregularly spaced, but regularly featured surface pits, sizes 0.2 and 0.5 μm, and regularly spaced pits with regular features (1 and 2 μm) diameter were produced.
Both aggregated and segregated (regularly spaced) distributions of wood were identified.
Many regularly spaced, sharp peaks appeared in the emission spectra of the Er2O3-doped glass microsphere.
3D-ZTA exhibit regularly spaced microporous, rough struts and fully interconnected macroporosity.
Land cover was recorded at 296 point locations regularly spaced on a 1 km grid.
One or both edges of the film are lined with regularly spaced perforations, or sprocket holes.
In ordinary crystals such a lattice image reveals regularly spaced rows of atoms.
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