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Novel oral anticoagulants have the potential to improve stroke prevention in patients who have atrial fibrillation and an elevated risk of stroke by overcoming several limitations of warfarin, such as the need for regular monitoring and dose adjustment, and the existence of multiple drug interactions and dietary restrictions.
However, VKA treatment involves regular monitoring and dose adjustment, owing to a narrow therapeutic window and an inherent variability arising from genetic and dietary factors.
Although effective, VKAs such as warfarin are not ideal for routine clinical use because of variability of dose response in individual patients (necessitating regular monitoring and dose adjustment), slow onset of action, and narrow therapeutic window [ 26, 27].
Similar(57)
Among these, parameters of drug exposure are most amenable to regular monitoring, and may potentially provide insight towards dose optimisation.
This is also subject to regular monitoring and review".
But he also called for regular monitoring and harsher penalties.
My role included visible involvement, regular monitoring and public recognition of successes and failures.
Regular monitoring and intensive monitoring are described in detail in the 'Monitoring protocols' section.
Regular monitoring and training of delivery ward staff continued throughout duration of the trial.
Regular monitoring and training of study staff continued throughout the duration of the trial.
Regular monitoring and retraining of the delivery ward staff continued throughout the duration of the trial.
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CEO of Professional Science Editing for Scientists @ prosciediting.com