The following covariates were considered in the regression: mechanism of injury (motor vehicle-related injury, other), age in years categorized (16 25 as reference group, 26 45, 46 and older), gender, education at follow-up categorized (below high school, high school, college and above as the reference group), an indicator for transfer to surgery from the ED,ISS, and RTS (Lichtveld et al. 2008).
Regularized logistic regression on mechanism strength scores and response calls from the four whole blood infliximab data sets produced a classifier model for anti-TNF non-response consisting of a linear combination of 18 mechanisms (Table 2).
Moreover, few regression-based studies look specifically for possible contingent relationships among explanatory mechanisms; regression analyses will typically assume that such interactions do not exist[ 47].
Interferon γ-induced protein 10 kDa (IP-10) is a potent chemoattractant and has been suggested to enhance antitumor activity and mediate tumor regression through multiple mechanisms of action.
All-trans retinoic acid and arsenic trioxide can act synergistically to cause leukemia regression through distinct mechanisms that lead to PML/RARa degradation, ultimately resulting in clinical remission of APL [30], [31].
Physiologically, the prerequisite of cell ECM adhesion interaction for cell cycle progression and cell survival is likely to be important in tissue morphology and regression as a mechanism to regulate tissue architecture and cell number.
Being the focus to assess the behaviour of the finite-rate mechanisms, fuel regression rate has been prescribed accordingly to available empirical data.
Abasic sites resulting from uracil-removal in single-stranded DNA at the replication fork could be handled by at least three different mechanisms; (i) regression of the replication fork and repair by short patch or long patch BER, (ii) recombination repair using the old strand at the other side of the fork, (iii) translesion DNA synthesis.
For simulated cyclic voltammograms based on the EC, Eqr, and EqrC mechanisms these regression algorithms in combination with nonlinear kernel/covariance functions yielded diffusion coefficients with higher accuracy as compared to the standard approach of calculating diffusion coefficients relying on the Nicholson-Shain equation.
This is, however, a field not widely explored and much remains to be learned about the mechanisms behind regression of cervical dysplasia.
