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79 Given that about half of trials remain unpublished, 80 81 82 and that published trials often represent a biased subset of all trials, 80 83 it is important that systematic reviews include a search of online resources such as trial registries, results databases, and regulatory agency websites.
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Data definitions are also consistent between the registries, resulting in a lower risk of misclassification bias for the variables studied.
Slovenia published a first report on its systematic audit from national registries resulting in an MMR of 9.8 per 100 000 for the period 1985 94.
To generate the dataset for the present analysis, a number of patients had to be excluded as a result of missing data in the contributing registries, resulting in a selection bias of patients.
Modular neck femoral stems have a higher-than-anticipated rate of failure in registry results, but large single-center cohort studies are lacking.
National joint registry results find that a certain group of patients has greater survivorship with resurfacing than with total hip replacement.
Registry results are influenced by confounding factors.
Increased clinician participation and collection of complete information will optimize the quality of Registry results and inform forthcoming analyses.
Finally, Belgian Reimbursement Registry results suggested DrotAA treatment was associated with a mortality reduction compared with Belgian patients not treated with DrotAA from the Promoting Global Research Excellence in Severe Sepsis (PROGRESS) database, after appropriate statistical adjustments for baseline differences [ 14].
Furthermore, the accuracy of registry results is not known; the surgeon may type the data into the wrong box on the form, or the register may enter wrong data into the database.
98, 99 Subsequent inclusion in a larger registry resulted in no such relative risk identified.
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