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The live imaging was done with 4×4 binning to minimize exposure time, photobleaching and registration artifacts.
An automatically generated skull mask was used to mask possible registration artifacts.
This procedure also minimized the influence of outliers that were due to registration artifacts.
The loss of HRV data was due to registration artifacts caused by body movements was also random and should not have affected the conclusions.
Our results indicate that even in the presence of registration artifacts the digital subtraction added information that was successfully incorporated during the feature selection process.
However, slight registration artifacts may still manifest in the images of the vasculature IPL-INL and INL-OPL, which may indicate that an additional correction factor is necessary.
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Third, DSCTA has faster scan acquisition and higher spatial resolution, allowing DSCT acquisition with minimal patient motion registration artifact and better visualization of mixed and noncalcified plaques in small vessels [ 14, 16].
Once registered to the midspace, the resulting individual functional sequences approximate the average size and shape of both experimental groups, limiting atrophy and registration-related artifacts.
The number of registrations when artifacts were present was relatively high (28.8% in non-intubated patients and 11.3% in intubated patients).
The simultaneous acquisition of data in this dual imaging setting will undoubtedly benefit image registration and reduce artifacts, and thus improve accuracy.
Furthermore, the 2-D registration could introduce artifacts into the image in the form of unwanted translational or rotational changes, as the they are not guided by 3-D contextual information.
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