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4) Regional variation sampling (REGVAR) maximizes the number of randomly chosen organizational health care regions (n = 7) included for each stratum, based on the assumption that there is considerable variation between regions that must be reflected in the sample.
Likewise, 45% of the LtoE-shifted regions (n = 751/1,717) overlapped with a TTR.
Differentially expressed genes (DEGs) were depleted within the LtoE-shifted regions (n = 249/1815, p < 2.2e−16) (Table 4, Supplementary Tables S8 and S9), and only a minority of them mapped within LADs (Fig. 5B).
Second, an NBS analysis including all atlas regions (n = 92) did not reveal any significant or trend-level connectivity decrease (nor increase) on the whole-network level (p > 0.5, NBS permutation test).
A two-stage stratified sampling method was used to select participants from these regions (n = 5460; 50.9% females; mean (SD) age: 40.8 (14.7) years).
We performed a proof-of-concept study by whole exome sequencing of multiple tumour regions (n = 22) from three patients with metastatic bladder cancer.
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The tertiary organization of GG-SpaD is a tandem assembly of three Ig-like domains, wherein a middle domain (M-domain) joins together the N- and C-terminal regions (N- and C-domains) of the pilin subunit (Fig. 1a, b).
Yang et al.40 concluded that the extra-ribosomal region of SecM has an arrest-reinforcing role, on the basis of the in vitro observations that sequence substitutions at the regions N-terminal to the originally determined "arrest sequence 23 of SecM impaired the arrest.
We clearly delineated the three structural regions (N-terminal, ACD, C-terminal) in each sequence.
Therefore, the protein can be considered composed by four different regions: N-terminal domain, allosteric site, catalytic core and C-terminal domain.
Sequences with a single ACD were selected based on their UniProt annotations (no fragment and protein existence level less or equal to 3) and then divided into three regions (N-terminal, ACD and C-terminal) from their ACD delineation.
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