One of these TS-clathrin mutants was a frameshift mutant [24] two were deletion mutants [23], [25] and one carried several point mutations [22], [38] but further analysis showed that glutamic acid (E1590) mutated to lysine within the trimerization region (hub) was the most important one for the TS-phenotype [36].
The London region (hub) had the lowest uptake (86.4%) and was also the most ethnically diverse (mean % non white 32.2% compared with mean 4.4% for all other hubs combined).
We also included indicators for geographical region (BCSP hub) to investigate regional variation in uptake.
What if people could do that in regions and "hubs" around the world, and what if we could connect all these hubs in way that serves a deeper global intention for profound personal and societal renewal?
It divides the UK into 30 regions, where hubs can be created, such as the home counties and north Wales.
But he added that the downtown Boston market, the region's hub, was still among the strongest in the nation.
The Kinokuniya Bookstore (in the mall at 1581 Webster Street; 415-567-7625) is a region-wide hub for those looking for hard-to-find publications, as well as English readers in search of titles in translation.
In the towns themselves, we found easygoing pubs that combine brews with views, like Grasshopper Pub, north of Halfmoon Bay in Madeira Park, and Lighthouse Pub, to the south in Sechelt, the region's hub.
Mostly done between different types of actors in a country, region or hub.
Below is a bustling hospital, the region's hub for transplant surgery.
