CNVs can alter chromosome structure by introducing additional large pieces of DNA into specific regions (duplications), or by positioning two different chromatin regions near to each other (deletions).
Regarding the H2-Q region, duplication is evident in approximately a 52-kb region from H2-Q4 to - Q10.
MtDNA sequence for Ramphotyphlops braminus is considerably smaller due to the absence of the control region duplication.
Also transposable elements can import new CREs into a promoter region, and other variation events can occur affecting the regulatory region (duplication, inversion, translocation).
Dot plot analyses suggest that retrotransposons served as substrates for NAHR in the most recent mouse Abp gene family region duplication.
The second coding region duplication is 4,580 bp long and comprises the 3′ end of the alternative transcript, Sap-r PA.
It has been hypothesized that some of these rate shifts are temporally (and possibly causally) associated with control region duplication and/or major changes in ecology and anatomy.
Strikingly, the phenotypes of the WBS region duplication and deletion are opposite to each other with respect to visuo-spatial and language abilities, as well as behaviour.
The gene duplication analysis showed that 58.5% and 6.3% of SlbHLH genes belonged to low-stringency and high-stringency duplication, respectively, indicating that the SlbHLH genes are mainly generated via short low-stringency region duplication in tomato.
