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"It is clear from the deteriorating macro environment and the competitive pricing environment in certain regions challenging profitability that we must embark on a more aggressive transformation," he said.
In contrast, many surprises have come from the study of non-protein-coding regions, challenging our understanding of mammalian gene expression.
The presence of multiple duplicated genes in NBS-LRR clusters makes these regions challenging sequencing targets.
Assembly and mapping: once sequencing is accomplished, the initial analysis of base calling is performed by proprietary software on the sequencing platform, followed by aligning the data to a known reference genome if available or by de novo assembly; short read lengths can make mapping in the repetitive regions challenging.
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It was decided seven minutes from the end by a try from a driving lineout and the scorer, given the backdrop to the game, was fitting: the Ospreys second row Ian Evans is off to Toulon next season as the regions, challenged financially, struggle to hold on to their best players.
An overt repudiation of the open market in a frantic Argentina would reverberate across the region, challenging uncertain democracies like those in Ecuador and Peru, while fanning the embers of anti-Americanism.
Results showed that the proposed CT synthesis algorithm based on a multi-atlas information propagation scheme and iterative process is able to synthesise pseudo CT images in a region challenging for registration algorithms.
For example, the Arctic is a region characterised by complex and incompletely understood climate processes, making climate modelling for this region challenging.
This potential coiled-coil domain is found to have a high tendency to self-associate, which renders the structural characterization of this region challenging (29).
Markers across the 5′ region of SNCA that were associated with increased odds ratio to develop PD are in almost complete linkage disequilibrium with each other, which makes pinpointing the biologically relevant variant within an associated 5′ region challenging.
Next the Ordos in the Huang He (Yellow River) region challenged the Oirat and warred successfully against the Ming.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com