Regional volumes were expressed in mm and the mean volume of each region calculated for control and Ppt1 −/− or nclf mice.
The RMS is defined as the number of sequences that contain the motif in the region over the number of sequences that were expected to contain the motif at the P-value cut-off level (random expectance of the motif occurring in that region calculated for 1,000 random sets).
The pairwise diversity for each of these regions was calculated for all pairs of genes and regions.
The normalized read counts in the peak regions were calculated for both samples for each peak region identified in either ASH patient or control, and peaks were ranked according to the difference in enrichment.
Substitution frequencies and stationary properties of genomic regions were calculated for 100 bootstrapped data sets, with the regions as units, to yield 95% confidence intervals.
In this work shutdown dose rates (SDR) for in-vessel and ex-vessel regions are calculated for maintenance purposes under a commercial irradiation scenario.
Estimates of synonymous and non-synonymous substitution rates for antigenic and non-antigenic regions were calculated for individual pairs of FMDV genomes.
The difference (d) between the mean log2 differential signals of flanking regions was calculated for every probe.
The mean immunoreactivity for tumour cells in central and peripheral tumour regions was calculated for each tumour.
From this, the average coverage across all the regions was calculated for each sample (Supp. Tables S3A and S3B).
