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The GLF covers England, Wales and Scotland only; therefore, the validation of the regional THIN prevalence data did not include data from Northern Ireland.
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There were minor differences in the spatial location of regional thinning across hemispheres, but generally the regions were quite consistent bilaterally.
Overall frontotemporal cortical thickness did not differ between groups, although regional thinning of the right superior temporal region was observed in patients.
Specifically, AD was characterised by regional thinning of the parahippocampal, subgenual cingulate regions and temporal pole, whereas cortical thinning in DLB was localised in the middle and posterior cingulate, superior temporo-occipital and lateral ortibofrontal regions.
By using regional thinning of the sole, easy flexion and extension of the toes is made possible.
Intriguingly, the loess on the Green Bay Lobe land surface is thicker than predicted by regional thinning trends from the Mississippi Valley and is geographically separated from much loess of southwest Wisconsin by a sandy region devoid of loess.
The spatial topography of regional thinning parallels that illustrated with the statistical map of Sample 1a alone (Fig. 2).
In a series of two patients, with inferior topographic steepening and regional thinning (less than 400 microns corresponding to the area of corneal steepening), CXL after customized epithelial removal was performed.
Lesions of the small coronary arteries or arterioles were recorded in approximately 20% of necropsy cases. 2 In chronic infarction, myocardial remodelling results in regional thinning of the myocardium.
The Rotterdam study has reported that lobar cortical thickness decreases with age 26; this study augments these findings by showing regional variation in thinning (see Fig 2) and that WMH, but not silent brain infarcts or microbleeds, has a mild effect on regional thinning (see Fig 3).
Our findings corroborate a previous study associating tic severity in adults with Tourette syndrome with regional cortical thinning in orbitofrontal regions (Peterson et al., 2001).
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