Sentence examples for regional mutations from inspiring English sources

Exact(2)

Alan Barrett of the University of Texas says travel by carriers of influenza, be they people in aeroplanes or birds on the wing, means regional mutations quickly spread around the world.

Mitochondrial heteroplasmy could also be caused by regional mutations or duplications of some mitochondrial copies [ 37, 38].

Similar(58)

The vast, presently unexplained, differences in mutation rates between loci (reviewed in [ 30, 73]) suggest the involvement of heterogeneous mutational mechanisms or regional mutation biases.

An important step toward understanding the causes of mutational heterogeneity would be to characterize regional mutation rates in a more diverse sampling of species.

These include hypermethylation at DNA promoter regions of genes involved in DNA repair, or direct control of regional mutation rates through chromatin organization [ 1, 50].

Investigating some 17 million single nucleotide variants from genomes of 562 tumors, it was shown that differential DNA repair, and not mutations, is the primary cause of large-scale regional mutation rate variations across the human genome [38].

Instead, these mutations occurred preferentially in structurally condensed lamina-associated heterochromatic domains, suggesting that chromatin organization is a factor that can bias the regional mutation rate in iPSC genomes.

We have termed the presence of regional mutation clusters kataegis (from Greek for shower or thunderstorm).

Are long chromosomes a requirement of the mechanism underlying regional mutation heterogeneity?

Thus these fungal species do not exhibit the regional mutation structure that has been observed in mammals.

As illustrated above, parameters to be taken into account are clinical diagnosis, onset age, family history, and regional mutation frequencies.

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