Such differences could be argued as relevant in explaining the detected regional effect: effective early detection translates into smaller size of the tumor, thus discarding the primary indication for NCS.
No significant correlations were observed in other regions, indicating a regional effect.
The regional effect is affected by regionally unique factors that cannot be expressed by national and compositional effects.
The top-ranking prefectures in terms of the rate of change attributable to the regional effect are in provincial regions, i.e., Yamaguchi prefecture, followed by Tottori, Ibaraki, Saga, and Ehime prefectures.
The regional effect shows the degree that region j's energy demand of user i exceeds the rate of change of the national energy demand of user i.
The differences in the regional effect rely on the differences in the regionally unique characteristics of each of the prefecture's energy users.
Further, the positive/negative state of the regional effect seems to be subject to whether the region is a big-city region or a provincial region.
Even though few IDO+ cells were found in the Foxp3+-rich paracortical regions of SLN, IDO depletes tryptophan and may have regional effect.
Accordingly, the obtained results suggest that it is possible to explain the differences between big-city and provincial regions, which are expressed as the regional differences of the regional effect, i.e., differences not in the production effect but in the energy-intensity effect.
The whole-genome additive effect was estimated by using all SNPs to construct the GRM, whereas the regional effect was estimated using only SNPs from a specific region to estimate a local GRM.
The Local Health Area variables included to capture fixed effects of regional context and health system resources had significant effects on the adjusted odds of registering for the Fair PharmaCare program; the most notable regional effect was that households situated in northern and remote regions were less likely to register for the Fair PharmaCare program (results not reported in Table 2).
