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Correction: May 26 , 2002 Sunday A map on May 5 with an article in some regional copies about a campaign to promote living in South Orange and Maplewood, N.J., misidentified a town adjoining South Orange to the north.
Correction: February 10 , 2002 Sunday An article in some regional copies last Sunday about the creation of luxury housing in Chicago referred incorrectly to a consultant who discussed the strength of the city's downtown market.
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Regional copy number of 3q26 increases in several cancers, such as head and neck, lung, and cervix [18], [19].
We have developed a method to detect associations of regional copy number abnormalities in cancer data.
Both chromosomal and regional copy number aberrations were detected in the tumor sample with the hallmarks of glioblastoma like EGFR amplification and chromosome 10 loss observed.
One consistent hallmark of human cancer genomes are somatically acquired genomic rearrangements, which may result in complex patterns of regional copy number changes [ 1, 2].
Chromosomal gain and regional copy number variation (CNV) have previously been reported for chromosome 8q, the genomic region containing ST18 (Guichard et al., 2012).
Building on the reverse in situ hybridization principle developed for chromosomal CGH [ 13], genomic microarray technology (aCGH; [ 14, 15]) now utilizes intensity values from up to millions of short DNA sequences to derive regional copy number estimates.
In general, two fundamental types are discernible: (a) regional copy number aberrations (CNAs), which are delineated by a gain or loss in the number of copies of a defined, subchromosomal region of DNA; and (b) structural rearrangements, which are defined by a change to the precise location or orientation of a given sequence of DNA.
Out of 18 places in the genome that showed regional copy number changes in the cancer sample by whole genome SNP typing, 6 of them harbored captured gene(s) and all except for one place agreed between the two datasets (Table 2).
Melton Mowbray pork pies have protected geographical indication status, which acts just like a trademark or appellation d'origine contrôlée and stops manufacturers from outside a region copying a regional product.
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