Sentence examples for regional binding from inspiring English sources

Fig. 6 Regional binding potential values (BP*ND) estimated by region-of-interest-based MRTMO with centrum semiovale as reference tissue in four subjects Fig. 7 Parametric images of BP*ND of the subject with lipophilic radiometabolites (NC2) created by voxel-based MRTMO using centrum semiovale as reference tissue.

The nature of specific regional binding of [F]FDOPA, predominately in the striatum region, was further validated by in vivo blocking studies.

Autoradiography experiments showed regional binding.

Table 5 Regional binding potential (BPND or DVR 1) estimates from the different methods for the tracer dose group (n = 10).

Thereafter, we initiated PET studies with arterial sampling in humans and used a single-tissue compartment model to estimate brain regional binding potentials [10].

By use of [11C]CHIBA-1001, the only α7-specific PET radiotracer tested in humans so far, only small regional binding differences of uncertain pharmacological specificity were detectable in the brain [16].

For determination of regional radioligand binding, regions of interest (ROIs) were manually delineated on each individual MR-image using the Human Brain Atlas software.

The regional cerebral binding of adenosine A2A receptor (A2AR) antagonists, [7-methyl-11C](E -8- 3,4,5-trimethoxystyryl -1,3,7-trimethylxanthine (11C-TMSX) [1] and 11C-KW-6002 [2],[3], wE -8- 3,4,5-trimethoxystyryl -1,3,7-trimethylxanthineman.

Interestingly, those three cases, all with different clinical presentations, differed markedly in regional H-THK5117 bintensitytensintensity

Regional H-THK5117 binding was highest in case one and lowest in case three.

Moreover, several PET studies also indicated gender differences in regional protein binding in the healthy human brain (19 22), while others found no such difference (23 25).