Stiffening also results in more rapid propagation of the arterial pulse pressure wave through the conductance arteries and can be readily assessed by measuring aortic pulse wave velocity (PWV; a marker of regional large artery stiffness) and central augmentation index (AIx; a composite marker of systemic arterial stiffness and left ventricular systolic loading).
We measured systemic (CI), regional (mesenteric artery; SMA) and microcirculatory blood flow (MBF) in 11 sedated and ventilated pigs.
Tbx1 affects asymmetric cardiac morphogenesis by regulating Pitx2 in the secondary heart field [ 44]; it also controls regional coronary artery morphogenesis [ 45], aorta morphogenesis [ 46], and blood vessel development [ 47].
Two ways of regional chemotherapy, hepatic artery infusion (HAI) and isolated liver perfusion (ILP), were compared investigating the difference in toxicity with tissue and biofluid concentrations of mitomycin C (MMC).
Systemic hemodynamics was evaluated by arterial and pulmonary artery catheters, while regional perfusion was assessed by portal vein blood flow (PVBF) and hepatic artery blood flow (HABF) with ultrasonic flow probes.
Route 517, off the I-78 exit, serves as a north-south artery for regional traffic.
Baseline values of mean maximal blood velocity (Vmean) in the middle cerebral artery (MCA), regional cerebral blood flow (rCBF), blood pressure, heart rate and pCO2 were recorded after 30 min of rest in the supine position in a quiet room.
Methods: An established model of ventilator-induced lung injury (VILI) was used (anesthetized pig) and all animals were monitored using esophageal manometry (Pes, pleural pressure), Electrical Impedance Tomography (EIT, regional ventilation) and pulmonary artery catheter.
We investigated regional changes in cerebral artery velocity during incremental exercise while breathing normoxia (21% O2), hyperoxia (100% O2) or hypoxia (16% O2) [n = 10; randomized cross over design].
Regional delivery of hepatic artery vasoconstrictors increase delivery of marker and may increase delivery of chemotherapeutic drug to liver tumour.
