While clinical data with CD95L and TRAIL are not yet available, TNF is a registered drug, albeit only for loco-regional application in a limited number of indications.
Therefore, it is of interest to further investigate the regional application of microbubbles in larger animals.
Using standardised diagnostic criteria and qualifiers facilitates soil correlation and technology transfer between countries and regions, which helps to better understand (relations between) soil resources and facilitates regional application of soil information, e.g. in land use planning.
This paper describes a systematic approach to eliciting such preferences, illustrated through a regional application of the Ocean Health Index in the California Current.
In addition, a regional application for chemotherapy prescription has been developed, based on a common guide for chemotherapy management ("Bonnes Pratiques de Chimiothérapie" Software) in order to harmonize management throughout the region.
In the Baltic Sea, recent policy-oriented actions toward regional application of an ecosystem approach to management of marine ecosystems are among the strongest in Europe.
Taking the above-mentioned dose-dependency of regional drug application in the scope of TACE as basis, one strategy to further improve the outcome of patients with advanced liver-limited or –predominant BTC and HCC may be the use of modern regional chemotherapy approaches in the scope of hepatic arterial infusion (HAI) [ 15, 16].
The classification scheme has been repeatedly utilized for global approaches with coarse resolution remote sensing data, while local or regional applications are still limited in number.
The option exists to include it, however, for example in regional applications (such as ARM) rather than on a meridian.
Despite growing concerns, challenges remain in estimating ET by remote sensing technology for regional applications, due to the difficulty in determination of aerodynamic, canopy and soil resistance.
