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These region-specific structure-function relationships support the hypothesis that disruption of white matter connections plays an important role in the pathogenesis of diabetes-related cognitive deficits.
Interestingly, FoxG1 appears not only to promote the proliferation of neural progenitor cells but also to specify region-specific structures within the developing telencephalon [ 82] and perhaps even neural lineage identity, as it was recently identified as a factor contributing to the direct reprogramming of fibroblasts to NSC-like cells [ 84].
Frequently, curators needed terms for the processes, margins, and regions of specific structures.
These gap-region related SVs indicate a specific structure of gap regions of the YH genome compared to the hg19 reference.
However, the analysis of the relative positions and orientations of the AuxRE/Y-patch coupling elements suggests that they are not just located in the same region, but also need a specific structure, namely directly oriented Y-patch overlapped with the direct AuxRE on its 3' flank or located 3' with a short spacer.
Our understanding of how DNA methylation and the histone code affect each other to differentially establish functional, region-specific chromatin structure is still in its early stages, but it is increasingly evident that these epigenetic marks are critical for genomic stability and disruption of these mechanisms contributes to a growing number of human malignancies.
Given that axons and dendrites have distinct roles in neuronal signaling, this uneven distribution of spectrin is likely to be one way in which these regions maintain the specific structures that support their individual functions.
However, no putative specific structure innervated by them could be identified in that region.
The products of these genes drive the region specific developmental program and lead to the formation of different adult structures.
The metric is region specific.
"It gives shape a specific structure.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com