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Low dosage regimens were reported [ 2].
All regimens were reported to be well tolerated.
Protease inhibitor (PI) based regimens were reported by 16 studies.
In TKR, diverse multi-modal regimens were reported.
In all, 34 regimens were reported with 151 different combinations of dose and schedule.
Ten first-line, 10 second-line and 12 third-line chemotherapy regimens were reported.
Similar(48)
Finally, a reduction in the use of obsolete ARVs in second-line regimens was reported during the period under study.
In the German study [ 21], a statistically significant longer survival for patients who received two or more trastuzumab-based regimens is reported.
The rate of severe diarrhea with the 2-week XELIRI or the FOLFIRI regimens was reported as 15% [ 15, 17], and we supposed that the rate with the wXELIRI regimen was, at most, 5%.
Recently, the efficacy of multiagent regimens was reported in two randomised controlled trials (Reni et al, 2005; Conroy et al, 2011); however, multiagent regimens have potentially increased adverse effects.
Similarly, a survival advantage with platinum-containing regimens was reported for patients with PDAC and a family history of any malignancy, in whom the status of BRCA mutation carrier status was not specified (Oliver et al, 2010).
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