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New dose regimens: With saquinavir, it was possible with phase IV studies to demonstrate that efficacy (in terms of viral load) achieved with a three-times-daily regimen was maintained by a twice-a-day regimen.
Furthermore, we found that the synergy of the TCAD regimen was maintained across multiple seasonal and avian influenza A strains, including the three major subtypes – A/H1N1, A/H3N2, and the avian A/H5N1 – that currently cause significant morbidity and mortality in humans.
This regimen was maintained for 9 weeks until primary tumors grew to approximately 1,800 mm.
The remifentanil/propofol treatment regimen was maintained for the first 3 days of the study.
This dietary regimen was maintained for 1 week before the study.
The antimicrobial regimen was maintained or adapted according to the results of susceptibility testing.
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How do you assess the appropriate de-escalated dose to ensure that the safety profile of the regimen is maintained?
However, data from a prior study indicate that the antiemetic efficacy of the aprepitant regimen is maintained over multiple cycles of chemotherapy.
Our results provide support that the efficacy of the short-term 25 Gy preoperative regimen is maintained if it is modified to hyperfractionation.
The blood levels following administration of the first of two tablets (at 12 h interval) in the emergency contraceptive regimen were maintained for a sufficiently long period of time to prevent further unwanted fertilization [ 24].
Stable antihypertensive regimens were maintained at least 6 weeks.
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