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Within 14 days after changing the injection site, her insulin regimen was changed to 12 units of glargine at bedtime and premixed insulin (lispro 50/50; mid mixture) before meals: 16 units before breakfast, 4 units before lunch, and 10 units before dinner.
On the advice of the on-call surgical team and the consultant microbiologist, the antibiotic regimen was changed to intravenous ceftazidine and metronidazole with oral cefalexin.
Therefore, the chemotherapy regimen was changed to GEM (1000 mg/m2, days 1 and 8) and TS-1 (a combination capsules of tegafur, gimeracil, and oteracil potassium, 60 mg/m2, daily, 2 weeks on/1 week off).
Owing to question about safety, the dosage regimen was changed, as follows: 5 mg (1 ml) of biperiden was diluted with 9 ml of saline resulting in a final dilution of 0.5 mg/ml.
Owing to the discovery of the additional metastasis, the chemotherapy regimen was changed to uracil and tegafur (UFT, 300 mg/body) and leucovorin (25 mg/body), which were administered daily (4 weeks on/1 week off), in Jan . 2010(2 years and 6 months post-surgery).
As he became bacteraemic after 3 days the antibiotic regimen was changed to amoxicillin and cefotaxime.
Regimen was changed to topical itraconazole and systemic intravenous itraconazole.
The patient's regimen was changed to kanamycin, moxifloxacin, ethionamide, para-aminosalicylic acid, and cycloserine.
At this point, the regimen was changed to cefotaxime and gentamicin.
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Those adverse effects may require that the drug dosage be reduced or the drug regimen be changed to make the drug tolerable to the patient.
The anti-TB regimen is changed after three months to rifampicin and isoniazid 7/7 because she accused arthralgias, tingling of the extremities, blurred vision and decreased visual acuity.
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