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Anyone can be better in a chosen sport with a well-rounded cross-training workout regimen, rather than excessive training in that activity alone.
This dosing regimen (rather than the more commonly used 40 mg/m2 every 3 weeks) was chosen based on phase I data in patients with advanced malignancy with no standard treatment options [26].
Vitamin A was given as the comparator regimen, rather than placebo, because the South African Department of Health guidelines recommend routine three-monthly vitamin A supplementation for children and clinics did not consistently provide vitamin A to children.
This may reflect the underlying reasons for conversion to an extended dosing regimen, rather than an inherent bias.
In so doing, this study goes beyond traditional guideline-concordant studies by examining antibiotic dose and regimen, rather than antibiotic choice alone.
It is unclear if etravirine can actually replace fully active compounds in a salvage treatment regimen rather than being added as another active component.
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HIV centers should also keep alternative antiretroviral drugs in stock so that clinicians can modify regimens, rather than interrupting them, during stock-outs.
The WHO recently updated guidelines on antiretroviral therapy for HIV infection in adults and adolescents [25] recommend that countries in sub-Saharan Africa should develop a plan to move towards zidovudine or tenofovir-based first-line regimens rather than stavudine-based regimen while the goal of this is to avoid drug toxicity.
However, we found that cisplatin-induced renal injury was shown with the same regimens rather than with different regimens.
Three RCTs involving patients with ischemic stroke used GKI regimens rather than only intensive insulin as their experimental treatment [ 65- 67].
Future studies may best be targeted at understanding the effect of pursuing different fluid balance regimens rather than monitoring techniques per se.
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