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Between these extremes, many insulin-treated participants had developed a simplified dietary regimen driven by a few rules of thumb.
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The survival curves in ECOG1684 5 separated well before a year, the planned duration of treatment, raising the possibility that the early very high dose component of the regimen drives its efficacy.
This stimulatory regimen drives CSR from IgM to IgG1, which is easily quantified by anti-IgG1 staining and flow cytometry (e.g., [5]).
It is quite possible that the typical OS exposure regimen drives steroid metabolism genes beyond the level necessary for osteogenesis.
Thus choice of regimen was driven to a large degree by the need to manage simultaneous tuberculosis (TB) and HIV treatment.
While all cause mortality also increased in the extended versus 12 month regimen comparison, driven by non-cardiovascular events, this study finding becomes mitigated by the inclusion of the landmark analysis at 12 months of patients enrolled in the PRODIGY trial.
To be clear: There is no proof that it was Walker's regimen that drove away Shane's and Shepherd's arthritis.
It is shown that it results in the design of a realistic dosage regimen which drives the immunological system close to the healthy equilibrium state.
To assess the 12-month efficacy and safety profile of an individualized regimen of ranibizumab 0.5 mg driven by stabilization criteria in patients with macular edema secondary to central retinal vein occlusion (CRVO).
Two main strategies are currently being exploited to eradicate the cancer stem cell (CSC) pool: i) chemotherapeutic regimens that specifically drive CSC into apoptosis and thereby deplete the CSC reservoir of the tumor, and ii) strategies aiming to drive CSC into differentiation and thereby increase their susceptibility to pro-apoptotic treatments [1].
The two main strategies that are currently being exploited to eradicate CSCs are (a) chemotherapeutic regimens that specifically drive CSCs toward cell death and (b) those that promote the differentiation of CSCs, thereby depleting the tumour reservoir.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com