This study shows that spraying HA using the wet coating method is a technique that can produce potentially bioactive bone-regeneration implants.
The trend is towards the use of biomaterials that promote corneal regeneration, with implants designed to mimic the corneal extracellular matrix.
These limitations have led to use of other potential sources and techniques such as stem cells, growth factors, and scaffolds to further enhance bone regeneration around implants and promote the osseous integration.
Self-assembled peptidic nanostructures have been studied by many research groups and found use as three-dimensional cell scaffolds for bone regeneration, dental implants, neural tissue engineering, biosensors for detection of viruses and other pathogens, antibacterial agents and in drug, protein and gene delivery.
Alveolar ridge reconstruction using iliac PCBM achieved sufficient vertical bone regeneration for implant placement.
To evaluate the efficacy of our printed tissue constructs for adipose tissue regeneration, we implanted them subcutaneously in mice.
Composite of synthetic octacalcium phosphate and collagen (OCP/Col) enhances bone regeneration if implanted into human, canine, or rodent bone defects.
This study suggests that the delivery of ASCs on ABB might effectively increase vertical bone regeneration and implant osseointegration, versus ABB alone.
Although in vivo studies in small animal model show the ligament regeneration by implanting mesenchymal stem cells (MSCs) and silk scaffold, large animal studies are still needed to evaluate the silk scaffold before starting a clinical trial.
This study shows an unprecedented biological activity for low-molecular-weight ligands on titanium, and gives striking evidence of the potential of these molecules to foster bone regeneration on implant materials.
Furthermore, bioactive groups can be incorporated into ELR peptides to obtain stronger and faster cell responses on tissues or coated biomaterial interfaces, thus promoting better regeneration or implant integration.
