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Methods: This system is characterised with regards to point and line sensitivity for typical detector settings in current clinical PET systems.
We have selected a stable Full-Length Infectious Clone (FLIC) of DENV-2 (gi:132271146; derived from a sylvatic DENV-2 strain P8 1407 isolated in Malaysia in 1970 24 as an input sequence to illustrate the capabilities of the GeneSV approach with regards to point mutation predictions and their characterization.
3) In regards to point 2 above, reviewers 1 and 3 point out that there is no demonstration that the breast cells overexpressing miR-142 eventually develop tumours or are more prone to getting tumours compared to wildtype cells.
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"My question is, we go to the video referee for every little decision with regards to points - why couldn't we go for that?
With regards to points 1 5 above, our previous paper in PLoS ONE [1] provided the first step in developing an intervention, demonstrating under experimental conditions that intrusive flashback memories were reduced by the visuospatial task Tetris [27], [28], [29].
In regard to point (1), laser pain was not significantly modified by motor cortex stimulation in normal subjects or migraine patients, despite a significant reduction of the evoked responses recorded from the vertex.
With regard to point (1), we agree with the reviewer that differences in urgency could affect the buildup rate calculation.
It differed from the 'full' or 'true' acupuncture intervention with regard to point location, needling depth, and the avoidance of 'de qi' and manual needle stimulation.
With regard to point (a), little experimental data is available for most kinases with regard to the sequence variability of substrates, structural detail of kinase-substrate complexes, kinetic or energetic aspects of the interaction.
The choice of trajectory termination criteria is further justified by the robustness of the reported results with respect to the detailed cutoff values, as discussed with regard to point (a).
With regard to point (2), one of the main reasons that response averages are not straight is the attrition of the trials with more extreme buildup rates from the averages.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com