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Significant variation still exists among units with regards to guidelines for both prevention and management of EI.
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We describe the single steps of what other organizations do in regards to guideline development and on what grounds they do it in other articles in this series (see [ 11] for a list of articles).
It has also been shown with regard to guidelines about prescriptions, that so-called 'don'ts' are better adhered to than 'dos'dos
Most studies that used psychological theoretical models for describing the behaviour of physicians with regard to guidelines, such as the TPB or the ASE model, concluded that the model used could only partly explain the variations in the adherence of the physicians to these guidelines [ 11, 18].
Besides, Tooher [ 55], reaches the conclusion that with regard to guidelines on pressure ulcers, the more comprehensive the implementation strategies are (that is, the greater the variety and breadth of the strategies) the more effective their implementation seems to be in the long term.
These three studies were all compromised by a small sample size or "unit of analysis" errors, and the conclusion was that insufficient evidence existed about the effectiveness of different implementation strategies with regard to guidelines aimed at nurses or allied health professionals.
Breast cancer care in Germany is highly standardized, not only with regard to guideline adherence and staffing, but also with regard to the emphasis on patient-centeredness, which is acknowledged and emphasized in the certification processes [ 34, 35].
Hence, it may be argued that Denmark has a more mature primary care system (with regard to guideline implementation and regulation), and we thus expected that GPs' attitudes to national clinical guidelines in the two countries somehow would reflect this development.
The type of vascular access for hemodialysis was less than optimal with regards to current guidelines.
Our hypothesis was that intermittent oral administration of alfacalcidol during HD sessions could be at least as effective as IV administration for SHPT control in regards to KDIGO guidelines [ 16].
Related to this, such a paradigm can also enable the accumulation of evidence from the actual use in practice with regards to adherence to guidelines and associate them with outcomes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com