Sentence examples for regardless of alterations from inspiring English sources

Position of variants in the array is fixed, regardless of alterations in the core repeat copy number.

In the present study, we observed that regardless of alterations in gene copy number, the expression of H2AX is regulated by miR-24-2.

Among them, 20% have a mutation in the gene encoding superoxide dismutase 1 (SOD1). 1 To date, over 160 mutations have been identified in SOD1, typically leading to a gain of toxic activity ultimately causing the degeneration of motoneurons, regardless of alterations in enzymatic activity.

Therefore, our study suggests a significant portion of HBV serologic outcome is determined by an individual's ability to mount an effective immune response at the time of HBV exposure, regardless of future alterations in immune status.

Regardless of their alterations, the ultimate fate of duplicated genes vary according to the individual plant and species [ 10, 11].

Patients with marker autoantibodies (n = 48, 67.6%) had a higher prevalence of impaired diffusing lung capacity for carbon monoxide (P = 0.0217) and increased serum levels of carboxyterminal propeptide of collagen I (P = 0.0037), regardless of capillaroscopic alterations.

Regardless of the functional alterations, we hypothesized that alterations of the renal transcriptome as a consequence of altered functions of Adamts16 could be important in understanding the potential link between the mechanism of action of this gene product and the physiology of BP regulation.

Regardless of mechanism, genetic alterations lead to tumor heterogeneity and provide advantages against drug treatment.

This emphasizes the importance of developing methods for identifying BRCA-like cancers, regardless of the underlying alterations [ 36].

Regardless of the specific alterations, their combined effects must also disable the mechanism of contact-dependent inhibition of proliferation, namely the cell's ability to prevent activation of the proliferation machinery in response to contact with neighbouring cells.

In the last two decades, progress in molecular biology have lead to a better understanding of sarcomas biology and ontology, though with limited therapeutic implications since the standard treatment of metastatic sarcoma remains chemotherapy, regardless of specific molecular alterations [ 5].