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Regarding translational research, data-driven and hypothesis-driven approaches appear not to be mutually exclusive, but largely complementary and reciprocally challenging.
A major paradigm shift is in order regarding translational research.
DR wrote background and conclusions regarding translational research projects and objectives.
We found no difference between liver IGF-I deficient and wild type mice regarding translational control of muscle protein synthesis.
The minipig genome sequence presented in this paper further augments the reliability of genome based predictions regarding translational research.
Based on these SDs, there was sufficient power to detect a significant left-right bias if mean side-to-side differences were >0.5 mm, regarding translational differences, and a significant left-right bias if mean side-to-side differences were >2.6°, regarding rotational differences.
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Rather, we should regard translational research as an integrated part of drug development during each phase of the programme.
Despite rapid advancements in the field of nanotechnology, there is mounting frustration in the scientific community regarding the translational impact of nanomedicine.
The field has seen many advances regarding pathophysiology, translational research, diagnostic accuracy, natural history and imaging, but successful treatment remains elusive.
To reliably assess therapeutic efficacy, knowledge regarding the translational model and the course of disease is needed.
Critical appraisal and expert consensus regarding these translational issues will go a long way towards fostering progress in the field.
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