Regarding the first aspect, over the past 30 years, vascular surgery has undergone a significant evolution process: all has changed with the advent of endovascular procedures and, thanks to the rapid evolution of available grafts, everything is still changing.
Regarding the first aspect, it is currently unclear whether CBCs usually evolve via two simultaneous changes on both sides of a helix, or instead represent the sum of two changes that occurred at different times, either as a series of two consecutive hCBC-type substitutions, or involving a non-paired intermediate state.
Regarding the first aspect, we showed that the nematode's development into adults differed significantly for (i) competition resulting from infection with aposymbiotic IJs of both nematode species without injection of bacteria and (ii) competition resulting from infection between symbiotic IJs of both nematode species.
As regards the first aspect, we observe that correction has significantly reduced the energy associated with the different modes embedded in the two analyzed signals.
As regards the first aspect, we acknowledge here that the recent versions of IGRF main filed models benefit from a much better geographical coverage as satellite data have been included in modeling.
As regards the second aspect, we see that the energy distribution with frequency does not change so much.
Regarding the second contribution, the use aspect-orientation improves maintenance and evolution of the non-functional requirements that are managed as aspects.
Regarding the second point we have amended the manuscript discussing the possibilities addressed by the referee but have also toned down the most speculative aspects.
With regard to the second aspect, both the presence of a greater thickness on the MALDI target due to the "rough" surface of the conductive tape and of the attached antenna, could affect laser focusing.
Regarding the third —and perhaps most important— aspect investigated, the one factor structure CFA (Model 3 in Table 4) effectively identified seven pairs of items involving correlated residuals, thus suggesting violation of local independence assumptions as well as content redundancies from the interpretative stance.
