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Based on our discussions, the individual reviews below and policy regarding submissions to eLife where additional significant experimentation is required, we regret to inform you that this submission of your work will not be considered further for publication.
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Please contact the editors at [email protected] regarding submission of such file types.
In addition, we discuss how recently introduced FDA standards regarding submission data and FDA guidance documents related to genomic and imaging data can be accommodated in a solution architecture for (surrogate) biomarker-based clinical development.
If you do not have an account, you will need to create one, but then can use this account for any future submissions to Science.At the manuscript submission and information portal, you will first accept terms regarding submission of a manuscript to Science.
All authors gave their final approval regarding submission for publication.
JBB, DP, EB, CL, JS, LF, and AD gave their final approval regarding submission for publication.
†Paperwork and procedures mean production and management of study documents regarding submission to institutional review board and completion of case report form.
I compare two possible extreme hypotheses regarding submission of papers to journals: the Q hypothesis, whereby the decision to submit is based on quality of research; and the P hypothesis, whereby it is based on probability of acceptance.
The most frequently cited desired lecture topics were statistical analysis, how to write a protocol, paperwork and procedures (production and management of study documents regarding submission to institutional review board and completion of case report form), and cost management in clinical research (Table 2).
Make sure to pay attention to the policy regarding "simultaneous submissions" and multiple submissions.
Apple's definition of morality is on display this week with a couple of changes to its policies regarding App Store submissions.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com