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Regarding prospective studies, primary outcomes were: all-cause mortality; CVD mortality; incident CVD including myocardial infarction and stroke; and incident DM using the same cutoffs as described previously.
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In this regard, prospective studies in which subjects were also phenotyped using a number of different clinical measures (e.g., lung function, BAL, etc).
Prior research has been limited in this regard since prospective studies of EGDT have reported significantly fewer proportions of patients either eligible for or receiving DO2 augmentation therapies as compared to the landmark EGDT trial [ 10, 31- 35].
It may lead to the development of validation or prospective studies regarding factors that may affect outcomes of RBC transfusion.
Even with the above limitations, this survey data can help researchers plan prospective studies regarding the usefulness of this test in TB-endemic areas in the future.
Although bloodstream infections (BSI) belong to the most important, frequent, and clearly defined infections encountered in ICUs, prospective studies regarding the incidence, prediction, and impact of delirium in association with BSI are not yet published.
Further studies regarding this issue, especially prospective studies, should be performed.
We did not find any controlled prospective studies regarding the efficacy of BFRs for pain.
Future prospective studies regarding CAs and cancer should be designed by taking into account the lifestyle and occupational/environmental exposures, along with factors of individual susceptibility.
There is limited information from large-scale prospective studies regarding the prediction of type 1 diabetes by specific types of pancreatic islet autoantibodies, either alone or in combination.
This in turn calls for further discussions and prospective studies regarding the safety and alternatives of these solutions in perioperative medicine.
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