Although extensive sequencing efforts have identified ∼2,000 mature miRNA sequences in human tissues, relatively little is understood regarding how small RNAs coordinately function in these cellular processes (Kozomara and Griffiths-Jones, 2011).
However, to date, there is still little evidence regarding how patients with small and medium pneumothoraces should be clinically managed [ 26].
While information exchange capability is a required feature of the certified electronic health record, we known little regarding how this technology is used in general and for pediatric patients specifically.
Despite recent advances, we still know surprisingly little regarding how and when these elements become active and proliferate in natural populations; the vast majority of elements remain transcriptionally and transpositionally quiescent during normal growth and development.
Historically there has been little agreement regarding how or whether this can be accomplished.
There is currently little evidence regarding how the role is perceived.
While the depth and quality of the board is largely dependent on the creativity (unspecified nor assessed) in the selection of images, there exists little research regarding how the creativity of the mood boards may be evaluated.
To date, however, no electrophysiological work has examined the letter spacing effect, resulting in little insight regarding how letter spacing impacts "hidden" levels of processing between apprehension of the word form and the final behavioral outcome.
However, there has been very little research regarding how different dosage forms transit through the gastro-intestinal tract in children compared to adults, due to both ethical and practical hurdles.
The flat dose-response curve and wide therapeutic index of SSRIs argue against a strong relationship between plasma levels and clinical response [34] and there is little evidence regarding how plasma levels of citalopram influence clinical efficacy [35].
